PMF isn’t a milestone, it’s a muscle, as you put it so well. But how often do we conflate PMF with momentum? Generative AI and ZIRP-era expectations have made this distinction unavoidable, pushing us to unlearn growth at all costs and rediscover true market resonance. Sustaining PMF, and evolving it daily, is the real test.
I think this is especially true for biotech and pharma since there's a regulatory barrier to even assessing if you have PMF. Clinical trials and convos with doctors/patients can act as a proxy but it's not the same feedback as SaaS where you can hear from users right after launching
PMF isn’t a milestone, it’s a muscle, as you put it so well. But how often do we conflate PMF with momentum? Generative AI and ZIRP-era expectations have made this distinction unavoidable, pushing us to unlearn growth at all costs and rediscover true market resonance. Sustaining PMF, and evolving it daily, is the real test.
I think this is especially true for biotech and pharma since there's a regulatory barrier to even assessing if you have PMF. Clinical trials and convos with doctors/patients can act as a proxy but it's not the same feedback as SaaS where you can hear from users right after launching